
Get a prescription for Doxylamine(Pyridoxine) online
Doxylamine/pyridoxine is a combination medication used to treat nausea and vomiting during pregnancy, commonly known as morning sickness.
Obtaining a Doxylamine (Pyridoxine) prescription online is simple; visit Your Doctors Online and connect with a doctor anytime, anywhere. Our online doctor will ask about your symptoms to determine treatment. They may suggest a follow-up appointment or clinic visit. Please know that a Doxylamine (Pyridoxine) refill will only be provided after a consultation with our doctor and if the medication is appropriate and safe.
What is Doxylamine (Pyridoxine)?
Pregnancy-related nausea and vomiting can be controlled with Doxylamine and Pyridoxine combination. Your health and nutrition throughout pregnancy may improve if your nausea and vomiting are reduced. Doxylamine is an antihistamine that may exert its effects indirectly by affecting the body’s endogenous chemicals (acetylcholine and serotonin) and acting on certain brain centers.
Uses of Doxylamine (Pyridoxine)
This medication combines doxylamine (an antihistamine) and pyridoxine (vitamin B6) to alleviate the symptoms of morning sickness during pregnancy, nausea and vomiting being the main ones. It is typically employed when other non-pharmacological interventions, like alterations to diet or way of life, have failed to resolve the condition.
How it works?
Doxylamine is an antihistamine that can help relieve nausea and vomiting by blocking the action of histamine in the body. It has sedative properties and may also help with sleep disturbances associated with pregnancy. Pyridoxine is a form of vitamin B6. While the exact mechanism of how it helps with morning sickness is not completely understood, it is thought to play a role in regulating neurotransmitters and hormones related to nausea and vomiting.
Different dosage forms of Doxylamine (Pyridoxine)
Doxylamine-pyridoxine is commonly available as delayed-release tablets designed to release the medication to provide more sustained relief gradually. It is marketed under brand names like Diclegis and Bonjesta.
How to use Doxylamine (Pyridoxine)?
Your healthcare provider will provide the dosing instructions for Doxylamine-Pyridoxine, which should be followed carefully. Typically, it is taken orally, with or without food. Taking the medicine before bedtime is best to help alleviate symptoms of morning sickness and counter the drowsiness due to the Doxylamine component.
Side effects of Doxylamine (Pyridoxine)
Some common side effects include:
- Drowsiness
- Wooziness
- Dry mouth
- Blurred eyesight
Some severe side effects that are uncommon but dangerous include:
- Allergic reactions
- Urinating difficulties
- Abnormal heartbeat
Request Doxylamine prescription online
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Hi Dr. Nicole, I’m 6 weeks pregnant and have morning sickness with nausea and vomiting. Can you please suggest some treatment?

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Prescription
- Doxylamine/pyridoxine, 10/10 mg
- Taken twice daily for 7 days.
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Precautions and Contraindications
- It is important to talk to your doctor before beginning any new medication during pregnancy so that they can provide you with individualized advice.
- The medication has serious interactions with Benzhydrocodone, Acetaminophen and Calcium/Magnesium/Potassium/Sodium Oxybates.
- It’s important to avoid potentially risky activities like driving or operating heavy machinery while under the influence of doxylamine due to the sedative’s sedative effects.
- Doxylamine-pyridoxine should be used with caution, if at all, by pregnant women who have certain medical conditions or allergies to any of the medication’s components.
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